COGNITIVE CONTROL TRAINING ENHANCES THE INTEGRATION OF INTRINSIC FUNCTIONAL NETWORKS IN ADOLESCENTS



Tailored tetravalent antibodies potently and specifically activate Wnt/Frizzled pathways in cells, organoids and mice

Secreted Wnt proteins regulate development and adult tissue homeostasis by binding and activating cell-surface Frizzled receptors and co-receptors including LRP5/6.The hydrophobicity of Wnt Caps proteins has complicated their purification and limited their use in basic research and as therapeutics.We describe modular tetravalent antibodies that can

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